Project Description

Amyloidogenic diseases, including dementia, are on rise with ageing world population. Therefore, amyloid detection system is needed. Studies show that large number of dementia caused solely due to amyloidogenic neurodegeneration. It is around 50 million people in 2019 and will be increased to 152 million by 2050. Although there are few processes currently under experiment to detect amyloid, requirement of large volume of clinical samples to perform analytical experiments have been a limiting factor. In this project, we will focus on developing a microfluidic device that has an amyloid specific fluorescent dye attached to its in situ fabricated porous polymer which is present in support to microfluidic device. We propose it to be a device to screen and detect amyloid proteins and peptides present in clinical samples.