Project Description

Microfluidics dealing with compound droplets have recently received much attention in the realm of cancer therapy. Compound droplet dynamics is relevant for Cancer cell sorting, separation, isolation, and cancer therapy. The mechanical behavior of cancer cells and their corresponding multiphase flow characteristics play a vital role in those medical applications. For instance, cancer cell deformation is a key parameter to distinguish between healthy and diseased cells for cancer therapy and to interrupt the metastatic process. In a confined flow, cancer cells may deform up to five times that of a healthy cell. The dynamics of compound droplets in microchannels, which mimic the movement of cancer cells in blood vanes, must be researched in order to shed further light on the practicality of microfluidic devices for cancer therapy. The project primarily aims to study the dynamics of deformation compound droplets in straight and curved microchannels both experimentally and numerically. Moreover, the project intends to study the behavior of compound droplets when they negotiate an obstruction